Lian Li Q58 Review: Best ITX Case Yet?
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Balancing looks and airflow just right
Editor’s Choice
(Image: © Niels Broekhuijsen, Tom’s Hardware)
Tom’s Hardware Verdict
Lian Li’s Q58 is capable of squeezing a high-TDP system into a small, 14.3 Liter ITX shoebox. And thanks to its half-glass, half-mesh panels, it’s thermally quite capable.
Pros
- +
+ Tidy, chic looks with both glass and mesh
- +
+ Great thermals thanks to mesh intake for the GPU
- +
+ Easy to build in
- +
+ Flexible build options, including ATX PSU
- +
+ Great finish quality
- +
+ Affordable at just $130
- +
+ Comes with PCIe 4.0 riser cable option for $30 extra
Why you can trust Tom’s Hardware
Our expert reviewers spend hours testing and comparing products and services so you can choose the best for you. Find out more about how we test.
Today’s best Lian Li Q58 and deals
$169.99
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Ten years ago, Lian Li was mostly known for extremely expensive aluminum cases that many dreamed of, but few could actually afford. But in the last few years, Lian Li has pivoted to become the people’s case maker. Gone is the requirement for everything to be aluminum – these days you’ll find plenty of steel, especially in the frames and mesh – but the design brilliance has remained, if not improved.
The company’s latest ITX case, the Q58, is an example of exactly this new way of thinking – it offers a brilliant design, oh-so-premium looks, and – get this – it only costs $130. If you’re familiar with the world of ITX cases, you’ll know that’s not a lot of money for a small, 14.3 liter case, especially with the likes of the NCase M1 costing around $210 and Louqe’s Raw S1 tallying in at a mighty $330.
So, without further ado, let’s dig in and find out if the Q58 is good enough for our Best PC Cases list.
It certainly has stiff competition, with both the Hyte Revolt 3 and Cooler Master’s NR200P impressing us on the compact case front in recent weeks.
- Lian Li Q58 at Amazon for $169.99
Specifications
Swipe to scroll horizontally
| Type | Mini-ITX |
| Motherboard Support | Mini-ITX |
| Dimensions (HxWxD) | 9.8 x 6.7 x 13.5 inches (250 x 170 x 342 mm) |
| Max GPU Length | 12.6 inches (320 mm) |
| External Bays | ✗ |
| Internal Bays | SFF PSU: 3x 2.5-inch + 1x 3.5-inch |
| Row 6 – Cell 0 | ATX PSU: 2x 2.5-inch |
| Expansion Slots | 3x Vertical |
| Front I/O | 1x USB 3. 0 |
| Row 9 – Cell 0 | USB Type-C |
| Row 10 – Cell 0 | Mic/Headphone Combo |
| Other | 3-Port Fan & RGB Hub |
| Front Fans | ✗ |
| Rear Fans | ✗ |
| Top Fans | Up to 2x 140mm |
| Bottom Fans | Up to 1x 120mm |
| Side Fans | ✗ |
| RGB | No |
| Damping | No |
Image 1 of 3
(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Circling around the outside of the chassis, the first thing that stands out about the Q58 is its simple design.
You’ll find half-height glass panels at the top, half-height mesh panels at the bottom, and an aluminum front panel that matches the rest of the case, with a finish split right in the middle.
Image 1 of 2
(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)
The case’s side panels are made of painted steel with a fine mesh that’s good enough to act as a rough dust filter, but the top panel is made from prettier anodized aluminum and has its mesh milled out. It’s a rougher mesh, but that’s okay as this is the exhaust location, so it doesn’t need to filter any air.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Flip around the back of the chassis, and there’s not much to be seen other than the motherboard’s IO cutout, three vertical expansion slots, a power socket, and a trio of thumbscrews. Front IO consists of a single USB 3.0 Type-A port, a USB Type-C port, and a mic-headphone combo jack.
But don’t be fooled by the tidy, simplistic exterior.
Hiding inside the Q58 has a very neat, surprisingly flexible design.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
First, lets talk about the panels a little more. The four side panels are all on hinges, and they are exchangeable. The default layout (and the layout I’d recommend), has the glass panels at the top with the mesh at the bottom, but you can opt to swap these around, or have all glass on one side and all mesh on the other. What you can’t do is have glass at the top of one side and the bottom of the other – the panels are mirrored, so their hinges won’t support this.
The one thing we do have to note about the panels is that two of them seemed awfully tough to slip from their hinges, though Lian Li informed us beforehand that this was an issue with our sample and that it would be fixed in retail cases.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
On the right side of the case you’ll find the main motherboard area. This fits an ITX motherboard mounted upside-down, and the bracket for the SFF PSU is installed from the factory.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Flip over to the left side, and you’ll spot the GPU area.
But if you look at the top of the chassis, you’ll spot a large cavity. Believe it or not, you can actually fit up to a 280 mm radiator up here, complete with fans. That’s honestly an amazing amount of cooling power for a case this small, and certainly something you should utilize given you don’t need any other layout.
The bottom of the case supports a single 120mm fan as intake underneath the PSU, though it does not ship with any fans. The bottom does have magnetic dust filters included in the accessory pack.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
At the back of the case, near the top, you’ll also spot a fan hub. This is a simple PWM & RGB hub with three ports – so it isn’t SATA powered, but it does offer a neat way to run all your fans and RGB devices through a single header. Given that most ITX motherboards only have one RGB header, and the case supports exactly three fans, this is a neat inclusion, especially at this price.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
For storage, you can fit up to three 2.5-inch drives in this chassis and one 3.5-inch drive. These are placed at the bottom, along the top radiator mount, behind the power supply; the last 2.5-inch slot is sneakily placed between the frame paneling at the front. It’s too tight there to get cables to, but Lian Li built in a hot-swap bracket. Keep in mind that the bottom drive only fits if you don’t install an intake fan.
The Q58 can support ATX PSUs
However, if you don’t want to invest in a pricey SFF or SFF-L power supply, Lian Li also includes a bracket to convert the chassis to ATX mode. In this mode, the Q58 will still happily swallow 320mm graphics cards, but you will be making a few sacrifices. For one, the biggest supported radiator drops from 280mm to 120mm, and storage options drop to just two 2.5-inch drives. So, for best results, we recommend sticking to an SFF power supply.
In its base variant, black with a PCIe 3.
0 riser cable, the Q58 costs $130. If you want a model that has a PCIe 4.0-capable riser cable because you’re dropping in an RTX 3000 or RX 6000 graphics card, this will run you an extra $30, bringing the price tag to $160. Meanwhile, the Q58 is also available in white – a finish that costs $10 extra on both the PCIe 3.0 and PCIe 4.0 variants.
Lian Li Q58: Price Comparison
$169.99
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Niels Broekhuijsen is a Contributing Writer for Tom’s Hardware US. He reviews cases, water cooling and pc builds.
Cooler Master NR200P Max Review: Plain ITX Brilliance
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If you just want a practical and effective ITX case, this is the one to pick up.
Editor’s Choice
(Image: © Niels Broekhuijsen, Tom’s Hardware)
Tom’s Hardware Verdict
Cooler Master’s NR200P Max takes the original NR200P, moves some stuff around, and throws in a mighty 280mm AIO and 850W SFX PSU for a stunningly practical end result.
Pros
- +
+ Includes pre-installed 280mm AIO & 850W PSU
- +
+ Standard with vertical GPU & PCIe 4.0 riser cable
- +
+ Easy to build in
- +
+ Great cooling
- +
+ Includes mesh and glass panels
- +
+ Tidy cable management (a rarity, for ITX)
Why you can trust Tom’s Hardware
Our expert reviewers spend hours testing and comparing products and services so you can choose the best for you. Find out more about how we test.
When NZXT came out with its h2 Mini-ITX enclosure, it impressed consumers and reviewers alike with its straightforward approach of including a PSU and AIO with the chassis, letting buyers divert their attention to picking the best internal components for gaming. Since then, few (if any) cases have gone in a similar direction. But today Cooler Master is here to offer up an alternative.
The chassis in question is called the NR200P Max, and it’s a variation of the original NR200P that, you guessed it, includes an AIO and a power supply – and not shoddy ones, either.
We’re talking about a massive 280mm CPU cooler and a powerful 850W SFX Juicebox. But the fun doesn’t end there – there is space to add plenty of drives, one or two additional fans, huge triple-slot graphics cards, and a PCIe 4.0 riser cable comes included because this case only supports vertical GPU layouts. Next to that, Cooler Master throws in not just a mesh side panel, but also a 4mm pane of tempered glass for when you want to get showy.
Given that the original NR200P was already quite good, especially at its price tag of $130 (and often discounted), there’s a lot to get excited about here – but there is a catch: The price is $349, and that’s before tariffs and freight costs – Cooler Master hasn’t been able to give me a final, on-the-shelf price tag to expect. Regardless, let’s dig in and find out if it’s good enough for our Best PC Cases list.
Specifications
Swipe to scroll horizontally
| Type | Mini-ITX |
| Motherboard Support | Mini-ITX |
| Dimensions (HxWxD) | 11. 5 x 7.3 x 14.8 inches (292 x 185 x 377 mm) |
| Max GPU Length | 13.2 inches (336 mm) |
| Included AIO | 280mm AIO |
| Included PSU | 850W SFX 80-Plus Gold |
| External Bays | ✗ |
| Internal Bays | 2x 3.5-inch |
| Row 8 – Cell 0 | 3x 2.5-inch |
| Expansion Slots | 3x Vertical |
| Front I/O | 2x USB 3.2 Gen1 |
| Row 11 – Cell 0 | Mic/Headphone Combo |
| Other | ✗ |
| Front Fans | ✗ |
| Rear Fans | ✗ |
| Top Fans | 2x 140mm |
| Bottom Fans | Up to 2x 120mm (One of which 15mm thick with GPU installed) |
| Side Fans | ✗ |
| RGB | No |
| Damping | No |
Features
Image 1 of 3
(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Starting with a quick tour around the outside of the chassis, you’ll notice that it’s really not all that exciting, at least as far as aesthetics go.
The case takes the ‘shoebox’ ITX case approach similar to the NCase M1 (and Shuttle well before that), albeit with a few differences and upgrades. The case is almost entirely made from painted SECC steel, and although the paint is applied to perfection with no bubbles or imperfections, it’s a bit boring.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
The chassis only comes in this Slate Gray color. The NR200P Max won’t come in black, white or any other color, and the paint is very flat – there is no texture. And with a light green tinge to it, it almost looks like something fished out of a WWII bunker.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
But it’s not all boring. Included with the chassis comes a tempered glass side panel, which should help the case look a lot better, especially with an RGB-packing system installed.
Image 1 of 2
(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Meanwhile, IO is provided up top by two USB 3.
0 ports and a headphone/mic combo jack, and the case has filters all around.
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
To open the chassis, simply pull the side panels off to remove them.
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(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Inside, you’ll find the large 280mm AIO installed at the top of the case, with extra-long hoses perfectly pre-routed for ideal placement. The 850W SFX PSU also comes pre-installed, with the cables mostly routed to the right places – and the cables are quite nice, actually. They are braided, which is almost overkill: As you’ll see later in the build, the GPU covers up so much of the system, you barely get to see any of it.
The NR200P Max fits standard Mini-ITX motherboards, has room for GPUs up to 13.2 inches (336 mm), and can fit up to three 2.5-inch drives and one 3.5-inch HDD – two if you sacrifice GPU length.
The bottom of the case has room to mount two 120mm fans, though with a GPU installed, the back fan will be limited to 15mm thick.
Includes a PCIe 4.0 Riser
(Image credit: Niels Broekhuijsen, Tom’s Hardware)
Cooler Master includes a cute riser cable, but you’ll definitely need it. The case only supports a vertical GPU mount, unlike the original NR200P, so the inclusion of a riser cable is a must. That it’s rated for PCIe 4.0 support is just a sweet extra, though I will be testing this claim at the end of this review.
With all that out of the way, let’s crack on with the build.
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Niels Broekhuijsen is a Contributing Writer for Tom’s Hardware US. He reviews cases, water cooling and pc builds.
O11 AIR MINI – LIAN LI is a leading supplier of
PC cases
EXTREME AIRFLOW
QUALITY MATERIAL
MODULAR BACK PLATE
9000 3 TO 6 SSD OR 4 HDD + 2 SSD
ATX PSU COMPATIBLE
TWO-CHAMBER DESIGN
GPU VERTICAL BACK (OPTIONAL)
9 0002
GERMAN ENGINEER
EXTREME AIRFLOW
SUPER FINE MESH FRONT, TOP AND SIDE PANELS
optimized for maximum airflow from all sides of the case at stable and low temperatures.
The ultra-fine mesh also acts as a dust filter, preventing dust from accumulating inside the case.
2 x 140 MM FRONT FAN
AND 1 REAR 120MM FAN INCLUDED
O11 AIR MINI comes with 2 front 140mm PWM fans and 1 120mm rear PWM fans pre-installed right out of the box. Speed up your system with ease.
SIZE COMPARISON
O11 AIR MINI vs. O11 AIR
AIR MINI is more compact than the original O11 AIR,
but the interior space is just as comfortable and improves cooling efficiency.
AIR COOLING OR…
O11 AIR MINI is ideal for air cooled systems as it has enough clearance up to 170mm for larger tower coolers.
WATER COOLING
The O11 AIR MINI is also water cooled AIO with enough space for 240mm or 280mm radiators top, side and bottom.
CONTINUOUS AIR FLOW FOR
AIR OR AHU COOLING UNIT
With an optimized mesh pattern on the front, top and side panels, the O11 AIR MINI provides exceptional focused airflow and overall system airflow for both air-cooled and AIO configurations.
The spacious interior allows for multiple fan or heatsink configurations to achieve maximum cooling temperatures.
AIR setting
Universal I/O 9 setting0036
MADE FROM THE BEST MATERIALS
O11 AIR MINI black is made from premium polished aluminum that looks as good as it feels. O11 AIR MINI white has a minimalist white powder coating. Durable tempered glass makes maintenance and display of internal components easy and worry-free.
MODULAR BACK PANELS FOR
COMPATIBILITY WITH ATX, M-ATX OR ITX MOTHERBOARDS
Includes 7 or 5 slot backplates. Back panel with 7 slots for ATX, M-ATX, ITX motherboards and back panel with 5 slots for M-ATX, ITX motherboards.
7 SLOTS
5 SLOTS
Previous
Next
Previous
Next
SUPPORTS STANDARD SIZE ATX PSU
9The 0002 O11 AIR MINI supports Full ATX power supplies up to 200mm long, making it easy to switch power from another system and run the most power hungry systems.
UP TO 6 SSDs OR 4 HDDs + 2 SSDs
All storage is hidden behind the motherboard tray.
A total of 6 x 2.5″ drives or 4 x 3.5″ + 2 x 2.5″ drives can be mounted using dedicated storage brackets.
DOUBLE-CHAMBER CABLE
The cables can be quickly passed through the rubber grommets into the second chamber. There are multiple attachment points and channels for Velcro straps to keep your cables tidy.
OPTIONAL ACCESSORIES
Vertical GPU – CAN BE USED IN HIGH OR LOWER MODE.
Vertical GPU Bracket can be used as top or bottom mode to provide clearance for fans and heatsinks.
Top mode
Top mode 60mm gap
(Ｃinstall 2 x 120mm fans under GPU)
Bottom mode
20mm gap 90 046 (No space for GPU fans)
Offset heatsink bracket – for 240mm top radiator
Offset bracket avoids conflict with the memory module when installing an ATX motherboard and top heatsink with fans.
Allow 240mm AIO to be installed on top of O11 AIR MINI in 7 slot mode.
DOWNLOAD
O11 Air MINI manual
Download CAD
SPECIFICATIONS
| PRODUCT NAME | O11 Air MINI | |
|---|---|---|
| MODEL | O11AMX | O11AMW |
| COLOR | Black | White |
| DIMENSION | (D) 400 x (W) 288 x (H) 384 mm | |
| MATERIAL | 4mm aluminum panel 0.8mm mesh panel 4.0mm tempered glass | |
| MOTHERBOARD SUPPORT | E-ATX (max. width 280 mm)/ ATX/ Micro-ATX/ Mini-ITX | |
| PSU SUPPORT | ATX (max. 200 mm) | |
| FAN INCLUDED | (Front) 2 x 140mm PWM fans (rear) 1 x 120mm PWM fan | |
| FAN SUPPORT | (Top) 120mm X3 / 140mm X2 (Side) 120mm X2 (Bottom) 120mm X2/ 140mm X2 (Front) 120mm X2/ 140mm X2 (Rear) 120mm X1 | |
| RADIATOR SUPPORT | (top) 240 mm or 280 mm (side) 240 mm (bottom) 240 mm or 280 mm (front) 240 mm or 280 mm | |
| DRIVE SUPPORT | 6 x 2. 5″ SSD or 2 x 2.5″ SSD + 4 x 3.5″ HDD |
|
| LENGTH SPACE GP | 362 mm | |
| CPU HEIGHT SPACE | 170 mm | |
| EXPANSION SLOTS | 7 or 5 (depending on rear panel) | |
| I/O PORTS | 2 x USB 3.0 1 x USB 3.1 Type-c 1 x HD Audio | |
| DUST FILTER | 1 × removable bottom dust collector | |
FEATURES
| PRODUCT NAME | |
|---|---|
| O11 Air MINI | |
| 900 39 MODEL | |
| O11AMX | O11AMW |
| COLOR | |
| Black 9 0192 | White |
| DIMENSION | |
| (D) 400 x (W) 288 x (H) 384 mm | |
| MATERIAL 90 190 | |
| 4mm aluminum panel Mesh panel 0.  8mm 4.0mm tempered glass |
|
| MOTHERBOARD SUPPORT | |
| E-ATX (max. width 280 mm)/ ATX/ Micro-ATX/ Mini-ITX | |
| PSU SUPPORT | |
| ATX (Max. 200mm) | |
| FAN INCLUDED | |
| (Front) 2 x 140mm PWM fans (Rear) 1 x 120mm PWM -fan |
|
| FAN SUPPORT | |
| (Top) 120mm X3 / 140mm X2 (Side) 120mm X2 (Bottom) 12 0 mm X2/ 140 mm X2 (Front) 120 mm X2/ 140 mm X2 (Rear) 120mm X1 |
|
| RADIATOR SUPPORT | |
| (Top) 240mm or 280mm (Side) 240mm (bottom) 240 mm or 280 mm (front) 240 mm or 280 mm |
|
| DRIVE SUPPORT | |
6 x 2. 5″ SSD or 2 x 2.5″ SSD + 4 x 3.5″ HDD |
|
| LENGTH SPACE GPU | |
| CPU HEIGHT SPACE | |
| 170 mm | |
| EXPANSION SLOTS | |
| 7 or 5 (depending on back panel) | |
| PORTS I/O | |
| 2 x USB 3.0 1 x USB 3.1 type-c 1 x HD Audio |
|
| 1 × removable bottom dust collector | |
How to choose a computer case: Full Tower, MIDI Tower, Micro ATX or Mini ITX
How to choose
- Posted by EuroCent team
17 Feb
What do we pay attention to when Want to buy or build a PC yourself? Of course, what processor and video card are installed in it, how much RAM and what drives are installed.
Next, pay attention to the motherboard and power supply and case. When choosing a case, the consumer pays attention to bright coolers and their color, but few people look at what material and how well the case is made, how well the cooling and ventilation are organized, whether there is a place for organizing cables, what material is used for the side wall and how comfortable will do the assembly in this case, lay everything and connect it.
When choosing a case, you need to carefully look at the form factor of the case (its dimensions), which will directly depend on the motherboard.
It all comes down to the motherboard
The main thing to consider when choosing a PC case is the size of the motherboard. The motherboard must match the selected case. You also need to decide on the components that will be in your assembly:
- processor
- processor cooling
- motherboard
- memory
- graphics card
- liquid cooling
- heatsink
The power supply, cooling fans, and the number of drives you can fit in a case are pretty standard, but it doesn’t hurt to check their specifications and to make sure that the components you select fit into the case.
Motherboard Form Factors
There are four motherboard form factors that vary in size. A Full Tower or Extended ATX case will fit all motherboards in a variety of form factors, but not vice versa. You don’t necessarily need a huge E-ATX tower if you live in a small apartment or have limited space under or on your desk.
Motherboard form factors and sizes are listed below, from largest to smallest:
- Extended ATX (E-ATX) 12″ x 13″ or 305mm x 330mm
- ATX 12″ x 9.6 or 305 mm x 244 mm
- Micro-ATX (M-ATX) 9.6″ x 9.6″ or 244 mm x 244 mm
- Mini-ITX (Mini-ITX) 6.7″ x 6.7 in. or 170 mm x 170 mm
PC Chassis Dimensions
Let’s take a look at the PC case options that fit the four motherboard form factors above.
- Full Tower or Extended ATX (E-ATX)
- Midi Tower (TX)
- Micro ATX
- Mini ITX
Full Tower or Extended ATX (E-ATX)
9000 2 The largest of all buildings The PC is a Full Tower chassis, also known as an Extended ATX (E-ATX) chassis.
Even if you don’t use an E-ATX motherboard, if you want to install multiple cooling fans, a CPU cooler heatsink, a full-sized graphics card, and a liquid cooling system, it doesn’t hurt to get an E-ATX case to spare the space. At this size, you don’t even have to worry about space to install hard drives or 2.5″ SSD drives.
Another reason to choose a Full Tower or E-ATX case is the extra depth to accommodate a long graphics card. High-end cards have been known to be large with their own cooling fans and can sometimes be up to 30cm long. Simply put, if you have one of these, you will need at least an ATX case. We recommend the E-ATX case if you are building a serious gaming PC based on an ATX or E-ATX motherboard.
MIDI Tower (ATX)
Midi Tower or sometimes known as Mid Tower is the most common PC case. Mid because it sits between the large Full Tower and the smaller Micro ATX Tower, a play on the word “medium”. It is designed for motherboards up to the ATX form factor, which means there will be plenty of room for ATX, Micro-ATX, or Mini-ITX motherboards.
Since this is the most common option, you will never run out of designs to choose from. Manufacturers also offer them at competitive prices, so you can buy a decent Midi Tower for very little money. Depending on the design, Mid Tower cases are unlikely to have room for a full 360mm radiator. At best, it will contain a 280mm liquid-cooling radiator, unless there is extra space in front of it.
Micro ATX (mATX) Chassis
This is the most common choice among desktop PC manufacturers such as Dell, HP and Lenovo. They are sometimes referred to as mATX, but don’t confuse it with the smallest Mini ITX case listed below. Micro ATX cases are actually larger than Mini ITX cases and will require a Micro-ATX or Mini-ITX motherboard.
If you are considering a mATX case for your gaming machine, be sure to check the size of your graphics card. More often than not, limited case space means you’re limited to mid-range or entry-level GPU cards. Also, you definitely won’t be able to fit CPU heatsinks or water cooling into it, so be prepared for limitations.
Also look out for large CPU coolers such as the tall tower fan and large heatsink. Again, there may not be enough “reserve” space. We recommend choosing a Micro ATX chassis for mid-range desktops with small to medium sized graphics cards and a standard CPU fan. For additional cooling, there may be room for one or two case fans on top of the standard rear fan.
Mini ITX Chassis (Small Form Factor)
Mini ITX chassis, sometimes known as small form factor. Things will be busy there, so careful planning will be required. Make sure you have a list of the PC components you want to cram into the case ahead of time. Check the internal dimensions to make sure there is room for them in the case. The main reason for choosing a Mini ITX chassis is that you made a conscious decision to start small, starting with a small Mini-ITX motherboard.
There will also be no room for additional cooling, let alone liquid cooling. Some cases have the option to add small cooling fans, but that’s the limit of cooling you’ll get.